Vaginal versus Obstetric Infection Escherichia coli Isolates among Pregnant Women: Antimicrobial Resistance and Genetic Virulence Profile

Autor: Sáez-López E, Guiral E, Fernández-Orth D, Villanueva S, Goncé A, López M, Teixidó I, Pericot A, Figueras-Retuerta F, Palacio M, Cobo-Cobo T, Bosch J, Soto SM
Rok vydání: 2016
Zdroj: PLoS One
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0146531&partnerID=40&md5=97e1e9a38dc3364d29bf5654dbf5a1c6
Popis: Vaginal Escherichia coli colonization is related to obstetric infections and the consequent development of infections in newborns. Ampicillin resistance among E. coli strains is increasing, which is the main choice for treating empirically many obstetric and neonatal infections. Vaginal E. coli strains are very similar to extraintestinal pathogenic E. coli with regards to the virulence factors and the belonging to phylogroup B2. We studied the antimicrobial resistance and the genetic virulence profile of 82 E. coli isolates from 638 vaginal samples and 63 isolated from endometrial aspirate, placental and amniotic fluid samples from pregnant women with obstetric infections. The prevalence of E. coli in the vaginal samples was 13%, which was significant among women with associated risk factors during pregnancy, especially premature preterm rupture of membranes (p
Databáze: OpenAIRE