Confirmed Invasive Pulmonary Aspergillosis and COVID-19: the value of postmortem findings to support antemortem management

Autor:	Santana, Monique Freire, Pivoto, Guilherme, Alexandre, Márcia A. Araujo, Baía-da-Silva, Djane Clarys, Borba, Mayla Gabriela da Silva, Val, Fernando Almeida, Brito-Sousa, Jose Diego, Melo, Gisely Cardoso, Monteiro, Wuelton Marcelo, Souza, João Vicente Braga, Pinheiro, Silviane Bezerra, Ferreira, Luiz Carlos Lima, Naveca, Felipe Gomes, Nascimento, Valdinete Alves, Corado, André Lima Guerra, Hajjar, Ludhmila Abrahão, Silva Neto, João Ricardo, Siva, George Alan Villarouco, Pasqualotto, Alessandro C., Lacerda, Marcus Vinícius Guimarães
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Aspergillus Postmortem evidence COVID-19 bacterial infections and mycoses skin and connective tissue diseases respiratory tract diseases
Zdroj:	Revista da Sociedade Brasileira de Medicina Tropical v.53 2020 Revista da Sociedade Brasileira de Medicina Tropical Sociedade Brasileira de Medicina Tropical (SBMT) instacron:SBMT Revista da Sociedade Brasileira de Medicina Tropical, Volume: 53, Article number: e20200401, Published: 03 JUL 2020
Popis:	We present postmortem evidence of invasive pulmonary aspergillosis (IPA) in a patient with severe COVID-19. Autopsies of COVID-19 confirmed cases were performed. The patient died despite antimicrobials, mechanical ventilation, and vasopressor support. Histopathology and peripheral blood galactomannan antigen testing confirmed IPA. Aspergillus penicillioides infection was confirmed by nucleotide sequencing and BLAST analysis. Further reports are needed to assess the occurrence and frequency of IPA in SARS-CoV-2 infections, and how they interact clinically.
Databáze:	OpenAIRE
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