Local Experience in the Treatment of Acute Non-Lymphoblastic Leukaemia
| Autor: | Bezwoda, W.R., Lynch, S.R., Sacks, P., Gale, Diana, Bothwell, T.H., Stevens, K. |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Zdroj: | South African Medical Journal; Vol 47, No 5 (1973) South African Medical Journal; Vol 48, No 5 (1974) |
| ISSN: | 2078-5135 0256-9574 |
| Popis: | Seventy-six patients suffering from various forms of acute non-lymphoblastic leukaemia were seen at the Johannesburg Hospital over an 8-year period. During this time various forms of therapy were used. Results with 6-mercaptopurine and prednisone were very poor, with less than 10% of patients achieving complete remission. Daunorubicin, when used alone, proved too toxic, but when given in a smaller dose with other agents, was more effective. The best results were obtained in 22 patients in whom a combination of daunorubicin and cytosine arabinoside was used. Complete remissions occurred in 9 patients and partial remissions in 2. The median survival of these 11 patients was 42 weeks. It is noteworthy that 3 of these patients were still alive one-and-a-half years from the time of diagnosis, and 1 of them is still in complete remission, two years after she was first treated.S. Afr. Med. J., 48, 963 (1974). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|