Clinical characteristics and laboratory findings of 252 Chinese patients with anti-phospholipid syndrome: comparison with Euro-Phospholipid cohort
| Autor: | Shi, Hui, Teng, Jia-Lin, Sun, Yue, Wu, Xin-Yao, Hu, Qiong-Yi, Liu, Hong-Lei, Cheng, Xiao-Bing, Yin, Yu-Feng, Ye, Jun-Na, Chen, Pojen P, Yang, Cheng-de |
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| Rok vydání: | 2017 |
| Předmět: |
Asian Continental Ancestry Group
Adult Male China Aging Adolescent Clinical Sciences Lupus Antiphospholipid Autoimmune Disease Antibodies Laboratory Databases Young Adult Clinical Clinical Research Humans Child Factual Aged Cohort Thrombosis Hematology Middle Aged Antiphospholipid Syndrome Immunoglobulin A Arthritis & Rheumatology Asians Immunoglobulin M Immunoglobulin G Female Symptom Assessment Anti-phospholipid syndrome |
| Zdroj: | Clinical rheumatology, vol 36, iss 3 |
| Popis: | This study aims to characterize the Chinese Han patients with anti-phospholipid syndrome (APS) and compare the data with those of the Euro-Phospholipid cohort. We conducted a single center study consisting of 252 patients with definite APS from 2000 to 2015. We analyzed the clinical and laboratory characteristics of our cohort and compared the data with those of the Euro-Phospholipid cohort. Our cohort consisted of 216 females and 36 males, with a mean age at entry into this study of 41years (range 11-74years). Of these patients, 69 (27.4%) patients had primary APS, and 183 (72.6%) had secondary APS (SAPS), including 163 (64.7%) patients had systemic lupus erythematosus (SLE). Thrombotic events occurred in 190 (75.4%) patients, and the most common ones were deep vein thrombosis (40.1%) and stroke (23.8%), which were similar to the reports of the Euro-Phospholipid cohort. In contrast, our cohort had less pulmonary embolism (6.7%). Among 93 females with 299 pregnancy episodes, the rates of early ( |
| Databáze: | OpenAIRE |
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