Hypermetabolism in Amyotrophic Lateral Sclerosis ptients; a confirmation by a study versus control and using different formulas for calculating theoretical resting energy expenditure level

Autor: Jésus, Pierre, Fayemendy, Philippe, Nicol, Marie, Sourisseau, H., Boirie, Yves, Walrand, Stephane, Coëffier, Moïse, Preux, Pierre-Marie, Marin, Benoît, Couratier, Philippe, Desport, Jean-Claude
Přispěvatelé: Neuroépidémiologie Tropicale (NET), Institut Génomique, Environnement, Immunité, Santé, Thérapeutique (GEIST), Université de Limoges (UNILIM)-Université de Limoges (UNILIM)-CHU Limoges-Institut d'Epidémiologie Neurologique et de Neurologie Tropicale-Institut National de la Santé et de la Recherche Médicale (INSERM), Service d'Hépato-Gastro-Entérologie et Nutrition [CHU Limoges], CHU Limoges, Service de Neurologie [CHU Limoges], Unité de Nutrition Humaine (UNH), Institut National de la Recherche Agronomique (INRA)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), Laboratoire de Biostatistique et d'Informatique Médicale, Université de Limoges (UNILIM), Service de l'Information Médicale et de l'Évaluation [CHU Limoges] (SIME), European Society for Clinical Nutrition and Metabolism, Unité de Nutrition Humaine - Clermont Auvergne (UNH), Institut National de la Recherche Agronomique (INRA)-Université Clermont Auvergne (UCA), Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut d'Epidémiologie Neurologique et de Neurologie Tropicale-CHU Limoges-Institut Génomique, Environnement, Immunité, Santé, Thérapeutique (GEIST), Université de Limoges (UNILIM)-Université de Limoges (UNILIM), Grelier, Elisabeth, Neuroépidémiologie Tropicale ( NET ), Institut Génomique, Environnement, Immunité, Santé, Thérapeutique ( GEIST ), Université de Limoges ( UNILIM ) -Université de Limoges ( UNILIM ) -CHU Limoges-Institut d'Epidémiologie Neurologique et de Neurologie Tropicale-Institut National de la Santé et de la Recherche Médicale ( INSERM ), Unité de Nutrition Humaine - Clermont Auvergne ( UNH ), Université Clermont Auvergne ( UCA ) -Institut national de la recherche agronomique [Auvergne/Rhône-Alpes] ( INRA Auvergne/Rhône-Alpes ), Université de Limoges ( UNILIM ), Service de l'Information Médicale et de l'Évaluation [CHU Limoges] ( SIME )
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: 39th Espen European Society for Clinical Nutrition and Metabolism Congress
39th Espen European Society for Clinical Nutrition and Metabolism Congress, Sep 2017, La Hague, Netherlands. 36 (Supplément 1), pp.S34, 2017, Clinical Nutrition
Popis: International audience; Rationale:In Amyotrophic Lateral Sclerosis (ALS) hypermeta-bolism is find in 50– 60%, defined as an excessive level of resting energy expenditure (REE) >10% of theoretical value. 1919 Harris and Benedict’ s (HB) formulas are the main ones used to obtain the theoretical values, but other predictive formulas are also used in current practice. The aim of the study was to assess the level of REE in ALS patients compared to control populationand using six predictive formulas of theoretical REE.Methods:Nutritional assessments were performed in ALS patient and in two control populations without hypermetabo-lism: (control 1 and 2). Weight, height and body composition by bioimpedance analysis were assessed. REE was measured (mREE) by indirect calorimetry and calculated (cREE) using1919 HB ’ s and 1984 HB’ s formulas, and World Schofield, De Lorenzo, Johnstone and Mifflin St. Jeor formulas. Mann-Whitney and Chi2 tests were used for statistical analysis.Results:315 ALS patients, 80 control 1 and 54 control 2 were analysed. mREE was 1,503 kcal/24 h in ALS patients, 1,220 kcal/24 h in control 1 and 1,344 kcal/24 h in control 2, higher in ALS patients vs. cREE with all formulas (p < 0.0001) and higher vs. control 1 and control 2 (respectively p < 0.0002 and
Databáze: OpenAIRE
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