Retrospective Study of Lyme Borreliosis Serologies in France: Evolution between 2007 and 2011

Autor: Chartier, Loïc, Trombert-Paolantoni, Sabine, Gonzalo, Sylvie, Ferquel, Elisabeth, Choumet, Valérie
Přispěvatelé: Epidémiologie des Maladies Emergentes - Emerging Diseases Epidemiology, Pasteur-Cnam Risques infectieux et émergents (PACRI), Institut Pasteur [Paris]-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Institut Pasteur [Paris]-Conservatoire National des Arts et Métiers [CNAM] (CNAM), Laboratoire CERBA [Saint Ouen l'Aumône], CHU Saint-Etienne, Département de Virologie - Department of Virology, Institut Pasteur [Paris], Choumet, Valérie, Institut Pasteur [Paris] (IP)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Institut Pasteur [Paris] (IP)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM), Centre Hospitalier Universitaire de Saint-Etienne [CHU Saint-Etienne] (CHU ST-E), Institut Pasteur [Paris] (IP)
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: JSM Tropical Medicine and Research
JSM Tropical Medicine and Research, JSciMed Central, 2017, 2 (1), pp.1013
JSM Tropical Medicine and Research, 2017, 2 (1), pp.1013
ISSN: 2010-2011
Popis: International audience; Lyme borreliosis is an infectious disease caused by bacteria belonging to the genus Borrelia, transmitted to humans by the bite of infected hard ticks of the genus Ixodes. National surveillance data are very scarce across Europe. Contribution of biology proves essential for diagnosis in the late manifestations. Our aim was to investigate the retrospectively frequency of Lyme positive serologies obtained from two French laboratories, their geographical distribution and their evolution over time. Sera tested were those received at CERBA between January 2007 and December 2011 and Biomnis between 2010 and 2011. IgG and IgM serum isotypes were detected by EIA. Antibodies specificity was analysed by western blot. Between 2010 and 2011, 83 528 patient samples were analyzed and 5 800 patients had positive serology for Lyme disease in France. The standardized rate of positive Lyme serologies (PLS) observed in our study was 4.63 cases per 100,000 person-year in 2010-2011. The regions localized at the center, the East and the NorthEast of France had a high incidence of PLS whatever the year. These areas have a dense forest cover. They represent a favorable habitat for ticks as well as for human outdoor activities. Prevention should be strengthened in these regions particularly in the elderly population. Percentage of positive patients over year was correlated with the annual temperatures, suggesting that climate change may impact Lyme incidence. A strong increase of the incidence was observed between 2010 and 2011 in six regions requiring an enhanced monitoring in the future.
Databáze: OpenAIRE
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