Development of Li+ Selective Microelectrode Using PPy [3,3'-Co(1,2-C2B9H11)2] as a Solid Contact

Autor: Merzouk, S., Zine, Nadia, Tahajanan, M., Agouzoul, M., Bausells, Joan, Teixidor, Francesc, Jaffrezic-Renault, Nicole, Errachid, Abdelhamid
Přispěvatelé: SIMS - Surfaces-(bio)Interfaces - Micro & Nano Systèmes (2011-2014), Institut des Sciences Analytiques (ISA), Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Instituto de Microelectrònica de Barcelona (IMB-CNM), Centro Nacional de Microelectronica [Spain] (CNM)-Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Institut de Ciència de Materials de Barcelona (ICMAB), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Bussy, Agnès
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Sensors & Transducers, Vol 27, Iss Special Issue, Pp 258-263 (2014)
MADICA 2012-8èmes journées Maghreb-Europe, Matériaux et Applications aux Dispositifs et Capteurs.
MADICA 2012-8èmes journées Maghreb-Europe, Matériaux et Applications aux Dispositifs et Capteurs., Nov 2012, Sousse, Tunisia
ISSN: 1726-5479
2306-8515
Popis: Planar all solid-contact ion-selective microelectrodes (ASC-µISEs) with a conducting polymer (polypyrrole doped with cobaltabis(dicarbollide) anion [3,3'-Co(1,2-C2B9H11)2]) as a solid contact layer between the polymeric membrane sensitive to lithium (Li) and the gold (Au) substrate were prepared and investigated. The N,N-dicyclohexyl-N',N'-diisobutylyl-cis-cyclohexane-1,2- dicarboxamide (ETH 1810) was used as ionophore for Li recognition. The developed microelectrodes show a linear response for Li+ concentration between 6´10-5 M and 1´10-1 M with slope of 53±1 mV per decade and exhibits remarkably enhanced selectivity for Li over other cations. The calibration plots using artificial serum containing three different levels of sodium chloride (NaCl) (135, 145 and 155 mM) as a background electrolyte were shown a linear response with a slope of 50 mV per decade in the clinical range of interest (0.7-1.5´10-3 M Li+). The developed microelectrodes will be used to determine Li+ concentrations in serum samples of manic-depressive patients under Li treatment.
Databáze: OpenAIRE
Externí odkaz: