Acute effects of aqueous leaf extract of Aspilia africana C.D. Adams on some haematological parameters in rats
| Autor: | Kazeem Ajeigbe, Enitan, S. S., Omotoso, D. R., Oladokun, O. O. |
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| Zdroj: | Scopus-Elsevier African Journal of Traditional, Complementary and Alternative Medicines; Vol 10, No 5 (2013); 236-243 |
| ISSN: | 0189-6016 |
| Popis: | Several medicinal plants have been documented for their haematological effects either at low or high concentration but very little is known about Aspilia africana. The aim of the study was to investigate the acute effects of aqueous leaf extract of Aspilia africana at different concentrations on some haematological parameters in rats. Following 14 days of oral administration of aqueous extract of A. africana, Haematocrit (HCT), Haemoglobin concentration (HB), Mean Cell Haemoglobin Concentration (MCHC), Red Blood Cell Count (RBC Count), Total White Blood Cell Count (Total WBC Count), Absolute Neutrophils count (NEUT#), Absolute Lymphocytes count (LYM#), Absolute Eosinophils Count (EOSIN#) and Absolute Monocytes (MONO#) were evaluated in twenty (20) male Wistar albino rats. The rats weighed 174±20g, and were randomly assigned into 4 groups viz: Group 1, Control; Group 2, 250mg/Kg/d aqueous extract; Group 3, 500mg/Kg/d aqueous extract; and Group 4, 750mg/Kg/d aqueous extract. HCT, HB, MCHC, RBC Count, Total WBC Count, NEUT#, LYM#, EOSIN# and MONO# were significantly increased (P |
| Databáze: | OpenAIRE |
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