| Autor: |
Gouet, P, Zientara, S, Grimes, J, Diprose, J, Malby, R, Burroughs, N, Mertens, P, Stuart, D |
| Jazyk: |
francouzština |
| Rok vydání: |
1999 |
| Zdroj: |
Virologie. 3(3) |
| ISSN: |
1267-8694 |
| Popis: |
The structure of the core of bluetongue virus has been determined to 3,5 Å resolution by x-ray crystallography. Solving such a structure composed of 1 000 proteins is a challenge. It necessitates close collaborations between crystallographers, virologists and electron microscopists. The core is made of a proteinic capsid, 700 Å in diameter, enclosing a double-stranded RNA genome and a set of proteins required for transcription. The crystallographic structure reveals how the proteins of the capsid self-assemble, to form 2 layers whose subunits are arranged on different quasi-equivalent lattices. Tubes of electron density are observed below this envelope, which can be assigned to the RNA genome. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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