| Autor: |
Palles, C, Tomlinson, I, Chegwidden, L, Gharahkhani, P, MacGregor, S, Vaughan, TL, Schumacher, J, Jankowski, J, Fitzgerald, R, Gockel, I, Buas, M, Knapp, M, Noethen, MM, Becker, J, Pharaoh, P, Whiteman, DC |
| Rok vydání: |
2016 |
| DOI: |
10.1016/s1470-2045(16)30240-6 |
| Popis: |
Esophageal adenocarcinoma (EA) is an often fatal cancer with rising incidence in the developed world. Barrett’s esophagus (BE) is a pre-cancerous metaplastic precursor of EA. We performed the first genome-wide association study (GWAS) meta-analysis for BE and EA to date, using 6,167 BE cases, 4,112 EA cases, and 17,159 unscreened controls, all of European descent. We identified eight new genome-wide significant associated (P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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