Murine stem cells and applications thereof

Autor:	Sánchez García, Isidro, Pérez-Caro, M., Voces, Felipe
Rok vydání:	2006
Zdroj:	Digital.CSIC. Repositorio Institucional del CSIC instname
Popis:	Filing Date: 2006-05-24.--Priority Data: EP 05076219.4 (2005-05-24) The invention relates to animal solid tumour models which comprise a transgenic non-human mammal containing in its genome a DNA construct that comprises a gene created and/or activated by a genetic anomaly associated with human cancer operatively bound to a promoter that directs the expression of the gene in Scal+ cells. The invention also relates to stem cells capable of specifically expressing in stem cells human genetic anomalies associated with human pathologies. Applications of these models and stem cells, such as diagnostic, therapeutic and prophylactic applications for human diseases, and products and methods are provided.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b0ce22ecbe582b3a2e568e35c1235eb6 http://hdl.handle.net/10261/2818 Zobrazit plný text záznamu