Photoprotective activity of Yucca periculosa polyphenols
| Autor: | Ana María GARCÍA-BORES, Christian BELLO, Yukiko CAMPOS, José del Carmen BENITEZ, Saul FLORES, Margarita CANALES, Tzasná HERNÁNDEZ, José Guillermo AVILA ACEVEDO |
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| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | Universidad Nacional Autónoma de México UNAM Redalyc-UNAM Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas (Chile) Num.2 Vol.9 |
| Popis: | "The aim of this work was to investigate the potential utility of the methanolic extract of the bark of Yucca periculosa, as well as trans-3,3',5,5'-tetrahydroxy-4'-methoxystilbene (MS), resveratrol, and naringenin for their potential as photochemopreventive agents. All substances have photoprotective effect against UV-B induced cell death in Escherichia coli, with MS and resveratrol showing the highest photoprotective properties. The sun protection factor (SPF) of the substances was evaluated by a guinea pig bioassay and a histopathological skin study. All substances prevented skin damage induced by UV and have an SPF higher than the octyl methoxycinnamate (OMC) a commercial sunscreen. The results showed the trans-3,3',5,5'-tetrahydroxy-4'-methoxystilbene isolated from Y. periculosa may afford substantial protection against the damages caused by UV exposure." |
| Databáze: | OpenAIRE |
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