The Rts1 regulatory subunit of PP2A is essential for septin organization in Candida albicans

Autor: Vázquez de Aldana, Carlos R., Orellana-Muñoz, Sara, Caballero-Lima, D., Correa-Bordes, Jaime
Rok vydání: 2020
Zdroj: Digital.CSIC. Repositorio Institucional del CSIC
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Popis: Trabajo presentado en el Simposio Internacional: Las levaduras: en la intersección de la biología de sistemas y la biomedicina/ Yeasts: at the cross-roads of Systems biology and Biomedicine, en memoria del Profesor Julio Rodríguez Villanueva, celebrado en Madrid (España), los días 23 y 24 de enero de 2020
Rts1 is the regulatory subunit of protein phosphatase 2A, sharing an overall identity of 47% with S. cerevisiae Rts1, although it contains an insert of around 100 amino acids located within the B56 regulatory domain, not present in ScRts1 was common in other fungal homologs, suggesting that they might have diverged from its S. cerevisiae counterpart to fulfil specific functions in the regulation of the PP2A phosphatase.
Databáze: OpenAIRE