| Autor: |
Nooy, A.E.J. de, Besemer, A.C., Bekkum, H. van |
| Přispěvatelé: |
Centraal Instituut voor Voedingsonderzoek TNO |
| Jazyk: |
angličtina |
| Rok vydání: |
1995 |
| Předmět: |
|
| Zdroj: |
Carbohydrate Research, 1, 269, 89-98 |
| Popis: |
With catalytic amounts of 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO) and hypochlorite/bromide as the regenerating oxidant in water, primary alcohol groups in glucans and derivatives thereof were rapidly and completely oxidised. For pyranosides, selectivity was higher than 95% and no side products could be detected with 1H and 13C NMR or with high-performance anion-exchange chromatography (HPAEC). The optimum pH for the reaction was between 10 and 11. The oxidation was found to be first order in TEMPO and Br-. The oxidation method can be applied to determine the amount of primary alcohol groups in water-soluble glucans; for pullulan, a proportion of 70% and for dextran, a proportion of 3% primary alcohol groups was found. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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