Cellular and molecular basis of adipose tissue development: from stem cells to adipocyte physiology
| Autor: | Louveau, Isabelle, Perruchot, Marie-Hélène, Gondret, Florence |
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| Přispěvatelé: | Physiologie, Environnement et Génétique pour l'Animal et les Systèmes d'Elevage [Rennes] (PEGASE), Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), AGROCAMPUS OUEST-Institut National de la Recherche Agronomique (INRA) |
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Animal biology
[SDV.SA]Life Sciences [q-bio]/Agricultural sciences [SDV.BA]Life Sciences [q-bio]/Animal biology Biologie du développement tissu adipeux Development Biology Cellules précurseurs Agricultural sciences Maturité tissulaire Alimentation et Nutrition Biologie animale cellule souche retard de croissance intrautérine Food and Nutrition [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition [SDV.BDD]Life Sciences [q-bio]/Development Biology Sciences agricoles RCIU |
| Zdroj: | Book of Abstracts of the 65th Annual Meeting of the European Federation of Animal Science 65. Annual Meeting of the European Federation of Animal Science (EAAP) 65. Annual Meeting of the European Federation of Animal Science (EAAP), Aug 2014, Copenhague, Denmark. Wageningen Academic Publishers, 20, 2014, Annual Meeting of the European Association for Animal Production 65. Annual Meeting of the European Federation of Animal Science (EAAP), Aug 2014, Copenhague, Denmark. Wageningen Academic Publishers, Annual Meeting of the European Association for Animal Production, 20, 2014, Annual Meeting of the European Association for Animal Production Book of Abstracts of the 65th Annual Meeting of the European Federation of Animal Science. (20)2014; 65. Annual Meeting of the European Federation of Animal Science (EAAP), Copenhague, DNK, 2014-08-25-2014-08-29, 82 |
| Popis: | White adipose tissue plays a key role in the regulation of energy balance in vertebrates. Its primary function is to store and release energy. It is also recognized to secrete a variety of factors called adipokines that are involved in a wide range of physiological and metabolic functions. Unlike other tissues, adipose tissue mass has large capacity to expand and can be seen as a dynamic tissue able to adapt to a variety of environmental and genetic factors. The aim of this review is to update the cellular and molecular mechanisms associated with adipose tissue growth and development in domestic animals, with a special focus on the pig. In contrast to other tissues, the embryonic origin of adipose cells remains the subject of debate. Among the variety of cell types contained in adipose tissue, we highlight recent data dealing with adipose-derived stromal stem cells that contribute to tissue homeostasis. The relationships between the proportions of the different stem cells and other molecular indicators of adipose tissue functions are investigated. The current knowledge on the dynamic expression of genes involved in cell cycle arrest, differentiation, and physiology during fetal development is summarized to determine how these changes may be linked to newborn survival. Both genetics and nutrients can affect these processes; they also influence the postnatal growth of adipose tissue. In brief, a better understanding of the developmental biology of adipose tissue is of great importance for targeting this tissue in the animal production held. |
| Databáze: | OpenAIRE |
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