IgE Sensitization to Thaumetopoea pityocampa: Diagnostic Utility of a Setae Extract, Clinical Picture and Associated Risk Factors
| Autor: | Vega, José María, Moneo, Ignacio, García-Ortiz, José Carlos, Rodríguez-Mahillo, Ana Isabel, Roques, Alain, Vega, Jesús |
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| Přispěvatelé: | Hospital Universitario Río Hortega, Partenaires INRAE, Instituto de Salud Carlos III [Madrid] (ISC), Unité de recherche Zoologie Forestière (URZF), Institut National de la Recherche Agronomique (INRA), URTICLIM, Agence Nationale de la Recherche (ANR 07BDIV 013), PCLIM-ACCAF/INRA |
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Pine processionary moth
[SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology Pine processionary caterpillar insect allergy [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie allergic reaction [SDV.IMM.ALL]Life Sciences [q-bio]/Immunology/Allergology [SDE.BE]Environmental Sciences/Biodiversity and Ecology human health immunoblotting allergen setae immunoglobulin E |
| Zdroj: | International Archives of Allergy and Immunology International Archives of Allergy and Immunology, Karger, 2014, 165 (4), pp.283-290. ⟨10.1159/000369807⟩ |
| ISSN: | 1018-2438 1423-0097 |
| Popis: | International audience; Background: Setae from Thaumetopoea pityocampa larvae (the pine processionary moth or PPM) can induce hypersensitivity reactions, but their clinical role in IgE-mediated responses is still subject to discussion. The aim of this study was to evaluate a setae extract for in vivo and in vitro diagnosis in nonhospitalized patients with reactions to PPM. Methods: Forty-eight adult patients presenting with PPM cutaneous reactions were studied by skin prick test (SPT) and specific IgE using setae and whole larval (WL) extracts. Biological standardized extracts were used for skin tests. Results: A total of 47.9% patients had a positive SPT for PPM (70% to both extracts, 17% only to the WL extract and 13% only to the setae extract). IgE immunoblotting detected several reactive bands in 91% of the SPT-positive cases. In multivariate analysis, male sex, immediate latency ( |
| Databáze: | OpenAIRE |
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