Poly(ether-ester-peptide) triblock copolymers: Synthesis and self-assembly behavior

Autor:	Tinajero, Ernesto, Martínez de Ilarduya Sáez de Asteasu, Domingo Antxon, Muñoz Guerra, Sebastián
Přispěvatelé:	Universitat Politècnica de Catalunya. Doctorat en Polímers i Biopolímers, Universitat Politècnica de Catalunya. Departament d'Enginyeria Química, Universitat Politècnica de Catalunya. POL - Polímers Industrials Avançats i Biopolímers Tecnològics
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	Enginyeria química [Àrees temàtiques de la UPC] Polymers Copolymers Nanoparticles Polypeptides triblock copolymers Polyglobalide self-assembly Pèptids Peptides PEG Polímers Copolímers
Zdroj:	UPCommons. Portal del coneixement obert de la UPC Universitat Politècnica de Catalunya (UPC) Recercat. Dipósit de la Recerca de Catalunya instname
Popis:	Triblock/grafted poly(ether-ester-peptide) copolymers made or PEG, poly(globablide) and poly(L-phenylalanine) were synthesized by sequential ROP starting from diaminated PEG as first initiator. The aromatic functionality of L-phenylalanine inserted on the globalide units was utilized to impart the amphiphilicity required to drive their self-assembly in water and to provide aromaticity of potential value for the efficient loading of aromatic drugs. Depending of the method used for preparation, nanoparticles possessing diameters between 25 and 600 nm were obtained by self-assembling in aqueous medium.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a2c1e8ae4365214dbdce1d7ac0ac3b73 http://hdl.handle.net/2117/135372 Zobrazit plný text záznamu