Desmoid tumors of the head and neck: A therapeutic challenge

Autor: Bree, E. de, Zoras, O., Hunt, J.L., Takes, R.P., Suarez, C., Mendenhall, W.M., Hinni, M.L., Rodrigo, J.P., Shaha, A.R., Rinaldo, A., Ferlito, A., Bree, R. de
Přispěvatelé: Otolaryngology / Head & Neck Surgery, CCA - Innovative therapy
Rok vydání: 2014
Předmět:
Zdroj: Head and Neck, 36(10), 1517-1526. Wiley Subscription Services, Inc., A Wiley Company Hoboken
de Bree, E, Zoras, O, Hunt, J L, Takes, R P, Suarez, C, Mendenhall, W M, Hinni, M L, Rodrigo, J P, Shaha, A R, Rinaldo, A, Ferlito, A & de Bree, R 2014, ' Desmoid tumors of the head and neck: A therapeutic challenge ', Head and Neck, vol. 36, no. 10, pp. 1517-1526 . https://doi.org/10.1002/hed.23496
Head and Neck : Journal for the Sciences and Specialties of the Head and Neck, 36, 1517-26
Head and Neck : Journal for the Sciences and Specialties of the Head and Neck, 36, 10, pp. 1517-26
ISSN: 1043-3074
Popis: Item does not contain fulltext Desmoid tumor, or aggressive fibromatosis, is a rare, histologically benign, fibroblastic lesion that infrequently presents in the head and neck. Desmoid tumors often grow locally, invasively, and may, in rare instances, be fatal secondary to invasion into critical structures, such as airway or major vessels. The most common treatment is surgery, but desmoid tumors are characteristically associated with a high local recurrence rate after resection. Although the margin status seems to be of importance, operations that avoid function loss and esthetic disfigurement should be the primary goal. The efficacy of postoperative radiotherapy is controversial. Its potential benefit should be carefully balanced against possible radiation-induced adverse effects. Alternative treatment modalities, such as primary radiotherapy and medical treatment or a wait-and-see policy, may be preferable to mutilating surgery. Considering all the aforementioned, it seems obvious that desmoid tumors of the head and neck present a therapeutic challenge and require an individualized approach. (c) 2014 Wiley Periodicals, Inc. Head Neck, 36: 1517-1526, 2014.
Databáze: OpenAIRE
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