Association between isolated female acne and insulin resistance: A prospective study

Autor: Kartal D., Yildiz H., Ertaş R., Borlu M., Utaş S.
Přispěvatelé: Kartal, D., Department of Dermatology and Venereology, Faculty of Medicine, Erciyes University, Kayseri, 38039, Turkey -- Yildiz, H., Department of Dermatology and Venereology, Nigde Hospital, Nigde, Turkey -- Ertaş, R., Department of Dermatology and Venereology, Kayseri Education and Research Hospital, Kayseri, Turkey -- Borlu, M., Department of Dermatology and Venereology, Faculty of Medicine, Erciyes University, Kayseri, 38039, Turkey -- Utaş, S., Department of Dermatology and Venereology, Fulya Acibadem Hospital, Istanbul, Turkey, 0-Belirlenecek
Jazyk: angličtina
Rok vydání: 2016
Předmět:
ISSN: 2637-3866
Popis: PubMed ID: 26373866
Background: acne is one of the manifestations of the polycystic ovary syndrome (PCoS). Nowadays hyperinsulinemia and insulin resistance are well-known characteristics of PCoS. the aim of this study was to investigate the relation between isolated female acne and insulin resistance and to determine the effect of hyperandrogenemia in this possible relationship. METHODS: Forty ive women with acne and 24 healthy women aged 25-40 were included in the study. The global acne grading system (GAGS) was used to evaluate acne severity. Blood samples were drawn for measurements of hormone proile, basal insulin and fasting blood glucose (FBG). the oral glucose tolerance test (oGtt) was performed on another day. homeostasis model assessment (Homa) score was used to assess insulin resistance (ir). all subjects underwent abdominopelvic sonography. reSUltS: thirty-six women with acne and 24 healthy women were analyzed after exclusion. Fifteen (42%) patients had moderate acne, 11 (30%) had severe acne and 10 (28%) had very severe acne. Basal insulin, FBG, AUC glucose, AUC insulin and HOMA values were signiicantly higher in patients with acne when compared with the control group (P
Databáze: OpenAIRE
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