Establishment of reference values for endocrine tests. III: primary aldosteronism
| Autor: | Baas, S. J., Endert, E., Eric Fliers, Prummel, M. F., Wiersinga, W. M. |
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| Přispěvatelé: | Endocrinology, Laboratory for Endocrinology, Faculteit der Geneeskunde |
| Jazyk: | angličtina |
| Rok vydání: | 2003 |
| Zdroj: | Netherlands journal of medicine, 61(2), 37-43. Van Zuiden Communications BV Scopus-Elsevier The Netherlands Journal of Medicine, 61(2), 37-43. Van Zuiden Communications BV |
| ISSN: | 0300-2977 |
| Popis: | Background: in our laboratory well-defined reference values for the screening test and confirmation test used in the diagnosis of primary aldosteronism were lacking. In this study we established the reference values of the plasma aldosterone concentration (PA), plasma renin activity (PRA) and PA/PRA ratio after a two-hour upright period, and of the urinary aldosterone excretion after oral sodium loading. Methods: Fifty healthy volunteers, equally distributed according to sex and aged between 20 and 70 years, went through the screening and confirmation test of primary aldosteronism. PA, PRA and the PA/PRA ratios were measured after a two-hour upright period (screening test). Urinary aldosterone excretion was determined in two 24-hour urine samples after an oral suppletion of 6 g NaCl a day for five days (confirmation test). Results: The following reference values were established: PA (after two-hour upright position) |
| Databáze: | OpenAIRE |
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