When observational studies are as helpful as randomized trials: Examples from orthopedic trauma : Examples from orthopedic trauma

Autor: Beks, R B, Bhashyam, Abhiram R, Houwert, R M, van der Velde, D, van Heijl, M, Smeeing, Dpj, Hietbrink, F, Leenen, L P H, Groenwold, Rhh
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: The Journal of Trauma and Acute Care Surgery, 87(3), 730. Lippincott Williams and Wilkins
ISSN: 2163-0755
Popis: Randomized controlled trials (RCTs) are often challenging to design in surgical fields and can be misleading when poorly executed. While the prevailing belief is that observational studies on therapeutic efficacy are credible only in exceptional circumstances due to unrecognized confounding, we identify three types of intervention in orthopaedic trauma and illustrate relevant features that allow observational studies in orthopaedic surgery to be as helpful as RCTs.
Databáze: OpenAIRE