Evaluation of Health-Related Quality of Life according to Carbohydrate Metabolism Status: A Spanish Population-Based Study
| Autor: | Vendrell, J., Vázquez, J.A., Valdés, S., Serrano-Rios, M., Rojo-Martínez, G., Pascual-Manich, G., Ortega, E., Mora-Peces, I., Menéndez, E., Martínez-Larrad, M.T., López-Alba, A., Gutiérrez, G., Gomis, R., Girbés, J., Gaztambide, S., Franch, J., Delgado, E., Catalá, M., Castell, C., Castaño, L., Casamitjana, R., Carmena, R., Bordiú, E., Bosch-Comas, A., Goday, A., Soriguer, F., Runkle, I., Fuentes, M., Calle-Pascual, A.L., Marcuello, C. |
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| Přispěvatelé: | Medicina i Cirurgia, Universitat Rovira i Virgili. |
| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | International Journal Of Endocrinology Repositori Institucional de la Universitat Rovira i Virgili Universitat Rovira i virgili (URV) |
| DOI: | 10.1155/2012/872305 |
| Popis: | 10.1155/2012/872305 Objective. To evaluate the association between diabetes mellitus and health-related quality of life (HRQOL) controlled for several sociodemographic and anthropometric variables, in a representative sample of the Spanish population. Methods. A population-based, cross-sectional, and cluster sampling study, with the entire Spanish population as the target population. Five thousand and forty-seven participants (2162/2885 men/women) answered the HRQOL short form 12-questionnaire (SF-12). The physical (PCS-12) and the mental component summary (MCS-12) scores were assessed. Subjects were divided into four groups according to carbohydrate metabolism status: normal, prediabetes, unknown diabetes (UNKDM), and known diabetes (KDM). Logistic regression analyses were conducted. Results. Mean PCS-12/MCS-12 values were /, respectively. Men had higher scores than women in both PCS-12 ( versus ; ) and MCS-12 ( versus ; ). Increasing age and obesity were associated with a poorer PCS-12 score. In women lower PCS-12 and MCS-12 scores were associated with a higher level of glucose metabolism abnormality (prediabetes and diabetes), ( for trend), but only the PCS-12 score was associated with altered glucose levels in men ( for trend). The Odds Ratio adjusted for age, body mass index (BMI) and educational level, for a PCS-12 score below the median was 1.62 (CI 95%: 1.2–2.19; ) for men with KDM and 1.75 for women with KDM (CI 95%: 1.26–2.43; ), respectively. Conclusion. Current study indicates that increasing levels of altered carbohydrate metabolism are accompanied by a trend towards decreasing quality of life, mainly in women, in a representative sample of Spanish population. |
| Databáze: | OpenAIRE |
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