Label free highly multimodal nonlinear endoscope using hollow core fiber
| Autor: | Rigneault, Hervé, Septier, D, Brévalle, Gaelle, Gajendra, Naveen, Saucourt, J, Bouwmans, Géraud, Cassez, Andy, Conforti, Matteo, Kudlinski, Alexandre |
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| Přispěvatelé: | Institut FRESNEL (FRESNEL), Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS), MOSAIC (MOSAIC), Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique des Lasers, Atomes et Molécules - UMR 8523 (PhLAM), Université de Lille-Centre National de la Recherche Scientifique (CNRS), Lightcore Technologies (LCT) |
| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Photonics West 2023 Photonics West 2023, Jan 2023, San Francisco, France |
| Popis: | We demonstrate a highly multimodal nonlinear micro-endoscope for real-time, label-free imaging of biological tissues. The endoscope can perform two and three photon excited fluorescence, second, third harmonic and CARS imaging for different excitation wavelengths. Ultrashort pulses are delivered to the sample by a double-clad antiresonant hollow core fiber over the 800-1800 nm spectral band. The fiber tip is placed into a doubly resonant piezoelectric tube which allows a spiral scanning on the sample. The endoscope distal head containing the scanning device and the GRIN micro-objective is 1.5 mm in diameter and 35 mm long. Real-time nonlinear imaging at 10 frame/s is demonstrated. |
| Databáze: | OpenAIRE |
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