| Popis: |
Background: Changes in osmolality (hyper- and hypo-osmolality) are associated with increased morbidity and mortality. However, stability of serum for measurement of this critical analyte is unknown. Our aim was to investigate the short- (8 hours) and long-term (1 month) stability of serum osmolality. Materials and Methods: Blood samples from 40 inpatients were collected in clot-activator tubes (Becton, Dickinson and Company, Franklin Lakes, USA) and centrifuged at 3220 g for 10 min (Hettich, Kirchlengern, Germany). Serum osmolality was measured in triplicate on OSMOMAT 3000 (Gonotech, Berlin, Germany) analyzer and mean values of the repeated measurements were used in the analysis. Primary tubes were left at room temperature (RT) for 8h, and aliquots were stored at -20°C for 1 month. Statistical analysis was performed using the MedCalc Statistical Software version 16.2.0 (MedCalc Software bvba, Ostend, Belgium). The results were tested with Friedman test. P value |
