QuantiFERON-TB Gold Plus Assay Specificity in Children and Adolescents With Suspected Tuberculosis-A Multicenter Cross-sectional Study in Spain

Autor:	Soler-Garcia, A, Gamell, A, Santiago, B, Monsonis, M, Cobo-Vazquez, E, Bustillo-Alonso, M, Tagarro, A, Perez-Gorricho, B, Espiau, M, Piqueras, AI, Korta-Murua, JJ, Rodriguez-Molino, P, Lobato, Z, Perez-Porcuna, T, Tebruegge, M, Noguera-Julian, A, Spanish Pediat TB Res Network pTBr
Rok vydání:	2021
Předmět:	pediatrics tuberculosis tuberculin skin test interferon-gamma release assay
Zdroj:	PEDIATRIC INFECTIOUS DISEASE JOURNAL r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu Fundació Sant Joan de Déu The Pediatric infectious disease journal r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe instname
ISSN:	0891-3668
Popis:	In this cross-sectional study of 284 children and adolescents with clinically or radiologically suspected tuberculosis in a low-endemic country, the QuantiFERON-TB Gold Plus assay specificity, sensitivity, positive predictive value and negative predictive value were 91.5%, 87.3%, 86.4%, and 91.2%, respectively. The specificity was higher than that observed in tuberculin skin tests performed simultaneously, but similar to previous-generation interferon-gamma release assays.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::90f7540c82b9db421d11ea78d92b46c1 http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=19891 Zobrazit plný text záznamu