Autor: |
F. D’Andrea, E. Venanzi Rullo, A. Marino, V. Moscatt, B. Celesia, B. Cacopardo, F. Condorelli, G. La Rocca, M. Di Rosa, G. Pellicanò, G. Nunnari, M. Ceccarelli |
Jazyk: |
angličtina |
Rok vydání: |
2020 |
Předmět: |
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Zdroj: |
World Cancer Research Journal, Vol 7 (2020) |
Popis: |
Combined Antiretroviral therapy altered the natural history of Human Immunodeficiency Virus (HIV) infection, leading to a substantial decline in morbidity and mortality of patients living with HIV. Due to the shared transmission routes, co-infection with HBV and HIV is not uncommon, especially in those patients with similar socioeconomic vulnerabilities and psycho-social conditions. HBV is a known cause of HCC even in absence of cirrhosis, and HIV-HBV-coinfected patients may have faster progression of hepatic fibrosis and a higher risk of cirrhosis and consequently HCC. In this article we review the epidemiology, the etiology, the role of coinfection HIV/HBV in the pathogenesis of liver cancer, the management and prevention of HBV infection in HIV-infected patients in the era of combined antiretroviral treatment. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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