| Autor: |
Ciruzzi, M., Schargrodsky, H., Rozlosnik, J., Pramparo, P., Delmonte, H., Rudich, V., Piskorz, D., Eva Negri, Soifer, S., Lavecchia, C. |
| Přispěvatelé: |
Ciruzzi M, Schargrodsky H, Rozlosnik J, Pramparo P, Delmonte H, Rudich V, Piskorz D, Negri E, Soifer S, LaVecchia C |
| Rok vydání: |
1997 |
| Předmět: |
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| Zdroj: |
Alma Mater Studiorum Università di Bologna-IRIS |
| Popis: |
The relation between family history of acute myocardial infarction (AMI) and the risk of AMI was analyzed using data of a case-control study conducted in Argentina between 1992 and 1994. Case patients were 1,060 subjects with AMI admitted to 35 coronary care units, and controls were 1,071 subjects admitted to the same network of hospitals where cases had been identified, for a wide spectrum of acute conditions unrelated to known or likely risk factors for AMI: 31% of cases versus 15% of controls reported greater than or equal to 1 first-degree relative with history of AMI. Compared with subjects without family history of AMI, the odds ratio (OR) of AMI, after allowance for age, sex, cholesterolemia, smoking, diabetes, hypertension, body mass index, education, social class, and physical exercise, was 2.18 (95% confidence interval [CI] 1.74 to 2.74) for those with family history of AMI. The OR was 2.04 (95% CI 1.60 to 2.60) for subjects with 1 relative, and 3.18 (95% CI 1.86 to 5.44) for those reporting greater than or equal to 2 relatives with AMI, in women the OR for any family history of AMI was 2.83, and in men 2.01. The association was of similar magnitude if the mother (OR 1.98), the father (OR 2.13), or a sibling (OR 2.48) had had an AMI. The association with family history was stronger at a younger age because the OR for subjects reporting greater than or equal to 2 more relatives with a history of AMI was 4.42 for subjects aged |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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