Application of different methods to formulate PEG-liposomes of oxaliplatin: Evaluation in vitro and in vivo

Autor:	Zalba, S. (Sara), Navarro-Blasco, I. (Iñigo), Troconiz, I.F. (Iñaki F.), Tros-de-Ilarduya, C. (Conchita), Garrido, M.J. (María Jesús)
Jazyk:	angličtina
Rok vydání:	2012
Předmět:	Oxaliplatin PEG-coated liposomes Heating method Reverse-Phase evaporation method Film method
Zdroj:	Dadun. Depósito Académico Digital de la Universidad de Navarra instname
Popis:	In this work the film method (FM), reverse-phase evaporation (REV) and the heating method (HM) were applied to prepare PEG-coated liposomes of oxaliplatin with natural neutral and cationic lipids, respectively. The formulations developed with the three methods, showed similar physicochemical characteristics, except in the loading of oxaliplatin, which was statistically lower (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::82ed1d48541802e65bb22aa6431d805a https://hdl.handle.net/10171/21016 Zobrazit plný text záznamu