Genetic control of vectors

Autor: Bouyer, Jérémy, Marois, Eric
Přispěvatelé: Animal, Santé, Territoires, Risques et Ecosystèmes (UMR ASTRE), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de la Recherche Agronomique (INRA), Réponse immunitaire et developpement chez les insectes (RIDI - UPR 9002), Université de Strasbourg (UNISTRA)-Institut de biologie moléculaire et cellulaire (IBMC), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Claire Garros, Jérémy Bouyer, Willem Takken and Renate C. Smallegange, Institut de biologie moléculaire et cellulaire (IBMC), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Bouyer, Jérémy, Claire Garros, Jérémy Bouyer, Willem Takken and Renate C. Smallegange, Institut National de la Recherche Agronomique (INRA)-Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Pests and vector-borne diseases in the livestock industry
Claire Garros, Jérémy Bouyer, Willem Takken and Renate C. Smallegange. Pests and vector-borne diseases in the livestock industry, 5, Wageningen Academic Publishers, pp.435-451, 2018, Ecology and Control of Vector-borne diseases, 978-90-8686-315-0. ⟨10.3920/978-90-8686-863-6_14⟩
DOI: 10.3920/978-90-8686-863-6_14⟩
Popis: International audience; In a context of tighter regulations on approved insecticide molecules, the spread of insecticide resistance in insect vectors of human and animal diseases and the introduction of exotic vectors to new territories call for the development of new pest control methods and strategies. New genetic control methods, related to the ancestral sterile insect technique (SIT), show particular promise and are being developed in response to increasing health and agricultural challenges. These include the use of symbionts like Wolbachia and the use of transgenic insect strains, some of which incorporate gene editing techniques that can lead to transgene spread (gene drive). Here we present the principles, associated opportunities and risks, as well as the degree of advancement of these various techniques for a subset of livestock pests and disease vectors including screwworms, tsetse, mosquitoes and stomoxes. We then present some case studies on recent improvements in the use of the SIT in tsetse and the release of insects carrying a dominant lethal gene, symbiont-based approaches and gene drive in mosquitoes. Finally, we call to speed up the development of genetic control, within a rigorous benefit-risk analysis framework including international public consultation.
Databáze: OpenAIRE
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