| Autor: |
Yilmaz, R., Yumusak, N., Polat, PELİN FATOŞ, Hitit, M., Yigin, A. |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Popis: |
The aim of the present study was to investigate the role of ADAMTS-7 gene in the pathogenesis of myocardial dystrophy associated with white muscle disease (WMD) in lambs. A total of 217 cardiac tissue samples from lambs with WMD were used in the study. Histopathological sections of the samples were stained with hematoxylin-eosin (HE) and examined using Western- blot, real-time PCR (RT-PCR) and immunohistochemistry for ADAMTS-7 gene expression, and the findings were statistically evaluated. Histopathological examinations revealed fibrosis associated with hyalinization, necrosis and granular calcifications in cardiomyocytes. Western blot and RT-PCR showed a statistically significant upregulation of ADAMTS-7 (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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