Supramolecular host-guest chemistry for applications in theranostics

Autor:	Spa, S.J.
Přispěvatelé:	Buchem, M.A. van, Leeuwen, F.W.B. van, Hoeben, R.C., Hage, J.A. van der, Bouwman, E., Velders, A.H., Cornelissen, B., Leiden University
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	Cyanine 5 Dyes Self-Assembly Far-red Fluorescence technology industry and agriculture macromolecular substances Theranostics Supramolecular Chemistry Host-guest Chemistry Bionanoparticles
Zdroj:	None
Popis:	The possibility of employing supramolecular interactions to solve theranostics challenges were discussed in this work. The possibility of utilizing supramolecular host–guest chemistry between β-Cyclodextrin and Adamantane to drive cell functionalization and cell–cell interactions in an in vitro environment was explored; the resulting pre-targeting set-up was further tested in vivo for liver radioembolization procedures. Furthermore, the self-assembly properties of ferritin were investigated to make a step towards the creation of new chemical entities that can be applied in precision therapy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7c820e820f3477d16443edcb63689530 http://hdl.handle.net/1887/72514 Zobrazit plný text záznamu