Supramolecular host-guest chemistry for applications in theranostics
Autor: | Spa, S.J. |
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Přispěvatelé: | Buchem, M.A. van, Leeuwen, F.W.B. van, Hoeben, R.C., Hage, J.A. van der, Bouwman, E., Velders, A.H., Cornelissen, B., Leiden University |
Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: | |
Zdroj: | None |
Popis: | The possibility of employing supramolecular interactions to solve theranostics challenges were discussed in this work. The possibility of utilizing supramolecular host–guest chemistry between β-Cyclodextrin and Adamantane to drive cell functionalization and cell–cell interactions in an in vitro environment was explored; the resulting pre-targeting set-up was further tested in vivo for liver radioembolization procedures. Furthermore, the self-assembly properties of ferritin were investigated to make a step towards the creation of new chemical entities that can be applied in precision therapy. |
Databáze: | OpenAIRE |
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