The multi-technique hard X-ray scanning imaging station of Nanoscopium possibilities for biological studies

Autor: Medjoubi, K., Baranton, G., Leroux, Vincent, Ribbens, M., Somogyi, A
Přispěvatelé: HAL-UPMC, Gestionnaire, Synchrotron SOLEIL (SSOLEIL), Centre National de la Recherche Scientifique (CNRS)
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: European Journal of Clinical Investigation
50th Annual Scientific Meeting of the European Society for Clinical Investigation Paris
50th Annual Scientific Meeting of the European Society for Clinical Investigation Paris, Apr 2016, Paris, France. pp.8.24
Popis: International audience; The Nanoscopium [1] 155 m-long nanoprobe beamline of Synchrotron Soleil (St Aubin, France) is dedicated to scanning multi-modal imaging in the 5-20 keV energy range. It aims to offer 2D/3D quantitative information on the elemental composition and morphology of the sample with high spatial resolution (down to 50 nm in 3D as ultimate goal) and analytical sensitivity i.e. trace, sub-parts-per-million (sub-ppm), detection limit. Application in biology, such as imaging of the metal concentration and distribution together with sample morphology, by coupling modalities such X-ray fluorescence, absorption, phase contrast and dark field, in tissues and cells will be carried out at Nanoscopium. In this talk, I will illustrate the proposed imaging techniques and their interest in biology through some examples.
Databáze: OpenAIRE