About the vibrational spectroscopy in the diagnosis of Alzheimer's disease | Sobre la espectroscopía vibracional en el diagnóstico de la enfermedad de Alzheimer
| Autor: | Carmona, Pedro, López-Tobar, Eduardo, Molina, Marina, Toledano Gasca, Adolfo |
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| Přispěvatelé: | Consejo Superior de Investigaciones Científicas (España) |
| Rok vydání: | 2015 |
| Zdroj: | Digital.CSIC. Repositorio Institucional del CSIC instname |
| Popis: | 6 pags.; 6 figs. Two-dimensional correlation vibrational spectroscopy is emerging as an alternative technique to detect relatively small alterations in composition and molecular structure of complex biological systems such as blood plasma resulting from pathological, physical and chemical processes occuring in body. In this paper the main concepts considered in the use of infrared and Raman spectroscopies in their two-dimensional form and their application in the search for markers for the diagnosis of Alzheimer's disease are described. Some examples of representation of spectral markers in ROC curves showing accuracies in classifications of samples greater than 80% are also discussed. Gran parte de los trabajos aquí mencionados han sido subvencionados con un proyecto del Plan Nacional 2009 y un proyecto INNPACTO 2012, así como con un Convenio/Contrato CSIC-Lab. Raman-Health. |
| Databáze: | OpenAIRE |
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