Cost-effectiveness of non-invasive assessment in the Dutch breast cancer screening program versus usual care: A randomized controlled trial

Autor: Timmers, J.M.H., Damen, J.A.A.G., Pijnappel, R.M., Verbeek, A.L.M., Heeten, GJ. den, Adang, E.M.M., Broeders, M.J.M.
Rok vydání: 2014
Předmět:
Zdroj: Canadian Journal of Public Health-Revue Canadienne de Sante Publique, 105, 5, pp. e342-7
Canadian Journal of Public Health-Revue Canadienne de Sante Publique, 105, e342-7
ISSN: 0008-4263
Popis: Item does not contain fulltext OBJECTIVE: Increased recall rates in the Dutch breast cancer screening program call for a new assessment strategy aiming to reduce unnecessary costs and anxiety. Diagnostic work-up (usual care) includes multidisciplinary hospital assessment and is similar for all recalled women, regardless of the radiologist's suspicion of breast cancer. This is similar in many Canadian settings. We developed a novel assessment strategy that offers women with a low suspicion of breast cancer a quick and non-invasive assessment by a screening radiologist (intervention). We compared these two strategies in a cost-effectiveness analysis based on a randomized controlled trial: multicentre randomized controlled trial (MASS trial, Netherlands National Trial Register: NTR1480). METHODS: Participants were enrolled between August 2010 and December 2012 and were randomly assigned to either the intervention or control group (allocation ratio 2:1). Fourteen assessment centres participated in the study. Questionnaires were used to record quality of life (EuroQol-5D), health care use and costs after recall. RESULTS: Our study comprised 366 women, of whom 288 were randomly assigned to the intervention group and 88 to the control group. The mean difference in cost was euro153/CAD $226 (95% confidence interval euro107-199/CAD $158-294, p
Databáze: OpenAIRE
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