Increased bile resistance in Salmonella enterica mutants lacking Prc periplasmic protease

Autor:	Hernández, Sara B., Ayala, Juan Alfonso, Rico-Pérez, Gadea, García del Portillo, Francisco, Casadesús, Josep
Rok vydání:	2013
Předmět:	animal structures Salmonella Prc protease Bile Peptidoglycan Penicillin-binding proteins
Zdroj:	Digital.CSIC. Repositorio Institucional del CSIC instname
Popis:	Prc is a periplasmic protease involved in processing of penicillin-binding protein 3 (PBP3). Lack of Prc suppresses bile sensitivity in Dam-, Wec-, PhoP-, DamX-, and SeqA- mutants of Salmonella enterica, and increases bile resistance in the wild type. Changes in the activity of penicillin binding proteins PBP3, PBP4, PBP5/6 and PBP7 are detected in a Prc- background, suggesting that peptidoglycan remodeling might contribute to bile resistance. Spanish Government; European Regional Fund (grants BIO2010-15023, BIO2010-18885, and BFU2009-09200); Consejería de Innovación, Ciencia y Empresa; Junta de Andalucía (grant CVI-5879); Spanish Ministry of Education and Culture
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7131b214acb475cffb60f0a5410311aa http://hdl.handle.net/10261/97731 Zobrazit plný text záznamu