Non-medical use of non-opioid psychotherapeutic medications in a community-based cohort of HIV-infected indigent adults
| Autor: | Vijayaraghavan, M, Freitas, D, Bangsberg, DR, Miaskowski, C, Kushel, MB |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Muscle Relaxants Statistics as Topic HIV Infections Opioid Medical and Health Sciences Cohort Studies Benzodiazepines Substance Misuse Non-medical use Clinical Research Humans Longitudinal Studies Prospective Studies Prescription Drug Abuse Prescription stimulants Central Poverty Prescription Drug Misuse Analgesics Psychotropic Drugs Psychology and Cognitive Sciences Neurosciences Substance Abuse Homeless Persons Middle Aged Alcoholism Cross-Sectional Studies Good Health and Well Being Ill-Housed Persons Central Nervous System Stimulants San Francisco Female Mental health Drug Abuse (NIDA only) |
| Zdroj: | Vijayaraghavan, M; Freitas, D; Bangsberg, DR; Miaskowski, C; & Kushel, MB. (2014). Non-medical use of non-opioid psychotherapeutic medications in a community-based cohort of HIV-infected indigent adults. Drug and Alcohol Dependence, 143(1), 263-267. doi: 10.1016/j.drugalcdep.2014.06.044. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/1sc3z1kv Drug and Alcohol Dependence, vol 143, iss 1 Vijayaraghavan, M; Freitas, D; Bangsberg, DR; Miaskowski, C; & Kushel, MB. (2014). Non-medical use of non-opioid psychotherapeutic medications in a community-based cohort of HIV-infected indigent adults. Drug and Alcohol Dependence. doi: 10.1016/j.drugalcdep.2014.06.044. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/488382vj |
| Popis: | Background: Non-opioid psychotherapeutic medications significantly increase the risk of opioid overdose-related deaths. We prospectively followed HIV-infected indigent adults sampled from the community to examine rates of and factors associated with non-medical use of benzodiazepines, muscle relaxants, and prescription stimulants. Methods: We interviewed participants quarterly for 2 years about alcohol and illicit substance use; depression; use of prescribed opioid analgesics, benzodiazepines and muscle relaxants; opioid analgesic misuse; and non-medical use (i.e., use without a prescription) of benzodiazepines, muscle relaxants, and prescription stimulants. Using mixed-effects multivariate logistic regression, we determined factors associated with non-medical use of benzodiazepines, muscle relaxants, and prescription stimulants. Results: Among the 296 participants at enrollment, 52.0% reported taking opioid analgesics that had been prescribed, 17.9% took benzodiazepines that had been prescribed, and 8.1% took muscle relaxants that had been prescribed. Over the 2-year study interval, 53.4% reported prescription opioid misuse, 25.3% reported non-medical use of benzodiazepines, 11.5% reported non-medical use of muscle relaxants, and 6.1% reported non-medical use of prescription stimulants. In multivariable analysis, opioid analgesic misuse in the past 90 days was associated with non-medical use of benzodiazepines, muscle relaxants, and prescription stimulants during the same time interval. Illicit substance use and depression were not associated with non-medical use of these medications. Conclusions: Prescription opioid analgesic misuse is associated with non-medical use of other psychotherapeutic medications. Health care providers should monitor for non-medical use of a broad array of psychoactive medications among high-risk populations to minimize harm. © 2014 Elsevier Ireland Ltd. |
| Databáze: | OpenAIRE |
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