Liječenje malih tumora bubrega ablacijskim metodama
Autor: | Ana Marija Alduk, Nikola Knežević, Luka Penezić, Tomislav Kuliš, Eleonora Goluža, Ivica Sjekavica, Željko Kaštelan |
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Jazyk: | chorvatština |
Rok vydání: | 2021 |
Předmět: |
tumori bubrega
ablacijske tehnike minimalno invazivni kirurški zahvati ABLATION TECHNIQUES – methods NEPHRECTOMY TUMOR BURDEN BOPSY RETROSPECTIVE STUDIES KIDNEY NEOPLASMS – diagnosis pathology surgery CARCINOM RENAL CELL - diagnosis pathology surgery RADIOFREQUENCY ABLATION MINIMALLY INVASIVE SURGICAL PROCEDURES –methods TREATMENT OUTCOME SURVIVAL ANALYSIS Deskriptori TUMORI BUBREGA – dijagnoza kirurgija patologija KARCINOM BUBREŽNIH STANICA – dijagnoza kirurgija patologija VELIČINA TUMORA ABLACIJSKE TEHNIKE – metode RADIOFREKVENTNA ABLACIJA MINIMALNO INVAZIVNI KIRURŠKI ZAHVATI – metode BIOPSIJA NEFREKTOMIJA ISHOD LIJEČENJA ANALIZA PREŽIVLJENJA RETROSPEKTIVNA ISTRAŽIVANJA |
Zdroj: | Liječnički vjesnik Volume 143 Issue 1-2 |
ISSN: | 0024-3477 1849-2177 |
Popis: | Mali tumor bubrega je radiološkim metodama utvrđena tvorba promjera do 4 cm. Kirurško liječenje je terapija izbora ovakvih tumora, ali se kod starijih bolesnika s komorbiditetima preporučuju i ablacijske metode. Cilj je ovoga rada prikazati naša iskustva liječenja malih tumora bubrega ablacijskim metodama. Učinili smo retrospektivnu analizu serije bolesnika liječenih radiofrekventnom i mikrovalnom ablacijom u Kliničkom bolničkom centru Zagreb u razdoblju od siječnja 2017. godine do kolovoza 2019. godine. Svim bolesnicima učinjena je odgovarajuća radiološka i preoperativna obrada, biopsija tumora i ablacija. Praćeni su prema standardnom protokolu radiološkim metodama 3, 6 i 12 mjeseci postoperativno te nakon toga jednom godišnje. Ablacija 32 mala tumora bubrega učinjena je kod 31 pacijenta, od čega 27 radiofrekventnih i 7 mikrovalnih ablacija. Jednogodišnje ukupno i tumor specifično preživljenje bilo je 100%, a kod 12,9% bolesnika utvrđen je rezidualni tumor. Troje ih je liječeno ponovnom ablacijom, a jedan radikalnom nefrektomijom. Imali smo četiri komplikacije iz 2. skupine po Clavien-Dindo klasifikaciji. Ablacijske metode su onkološki dobra i sigurna terapija kod bolesnika koji nisu pogodni za kirurški zahvat. Small renal tumor is a radiologically detected renal mass up to four cm in diameter. Surgery is the main therapeutic option in the treatment of these tumors, but in elderly and comorbid patients ablative techniques are the alternative. The aim of this paper is to report our experience in the treatment of small renal tumors with ablative techniques. We retrospectively analyzed patient records of individuals treated with radiofrequency and microwave ablation at the University hospital center Zagreb in the period from January 2017 to August 2019. An appropriate radiological and preoperative work-up was performed for all subjects, and then tumor biopsy and ablation. Patients were followed using the standard follow-up schedule: three, six, and 12 months after the procedure, and then annually, using radiological methods. Ablation of 32 small renal tumors was performed for 31 patients, 27 of which were radiofrequency and seven microwave ablations. One-year overall and cancer specific survival was 100%. In 12.9% of patients a residual mass was diagnosed – three were retreated with ablation and one underwent radical nephrectomy. We had four ClavienDindo grade 2 complications. Ablative techniques are an oncologically effective and safe treatment option for patients that are unfit for surgery. |
Databáze: | OpenAIRE |
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