SPECIFIC-INHIBITION OF GLYCOGEN-PHOSPHORYLASE BY A SPIRODIKETOPIPERAZINE AT THE ANOMERIC POSITION OF GLUCOPYRANOSE

Autor: Krulle, T, Watson, K, Gregoriou, M, Johnson, L, Crook, S, Watkin, D, Griffiths, R, Nash, R, Tsitsanou, K, Zographos, S, Oikonomakos, N, Fleet, G
Rok vydání: 1995
Zdroj: Tetrahedron Letters 36:45(Nov1995):8291-8294
ISSN: 0040-4039
Popis: A key intermediate bicyclic lactone 6 allows control of the anomeric configuration of a spirodiketopiperazine of glucopyranose 5 which is a specific inhibitor of glycogen phosphorylase, showing no inhibition of α- and β-glucosidases, α- and β-galactosidases, β-N-acetylglucosaminidase, pectinase, xylanase or cellulase. © 1995.
Databáze: OpenAIRE