Protective role of Syzygium cumini leaf extracts against paraquat-induced oxidative stress in superoxide-dismutase-deficient Saccharomyces cerevisiae strains
| Autor: | Soares, Jefferson de Jesus, Rosa, Anderson da Silva, Motta, Paola Ribeiro, Cibin, Francielli Weber Santos, Roehrs, Rafael, Denardin, Elton Luís Gasparotto |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Acta Scientiarum : Biological Sciences, Vol 41, Pp e47139-e47139 (2019) Acta Scientiarum. Biological Sciences; Vol 41 (2019): Publicação contínua; e47139 Acta Scientiarum. Biological Sciences; v. 41 (2019): Publicação contínua; e47139 Acta Scientiarum Biological Sciences Universidade Estadual de Maringá (UEM) instacron:UEM |
| ISSN: | 1679-9283 1807-863X |
| Popis: | The aim of this study was to evaluate the protective effect of three different extracts prepared from Syzygium cumini leaves against paraquat-induced toxicity in Saccharomyces cerevisiae strains deficient in superoxide dismutase (SOD). Additionally, the extracts phenolic and flavonoid contents, in vitro antioxidant activity, and phytochemical composition (using high-pressure liquid chromatography) were determined. Bioactive compounds from S. cumini leaves were extracted with infusion (traditional method) or ultrasound (aqueous or hydroalcoholic). Compared to the infusion extract, the ultrasound extracts exhibited a greater protective capacity against paraquat toxicity in the yeast cells as well as higher antioxidant activity. These results may be directly related to the higher phenolic and flavonoid contents in these extracts, since they are recognized as having high antioxidant actions. |
| Databáze: | OpenAIRE |
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