Heart rate at hospital discharge in patients with heart failure is associated with mortality and rehospitalization
| Autor: | Laskey, Warren K, Alomari, Ihab, Cox, Margueritte, Schulte, Phillip J, Zhao, Xin, Hernandez, Adrian F, Heidenreich, Paul A, Eapen, Zubin J, Yancy, Clyde, Bhatt, Deepak L, Fonarow, Gregg C, AHA Get With The Guidelines®‐Heart Failure Program |
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| Rok vydání: | 2015 |
| Předmět: |
Male
Heart Failure Cardiorespiratory Medicine and Haematology AHA Get With The Guidelines®‐Heart Failure Program Cardiovascular Patient Readmission mortality Patient Discharge Heart Disease Good Health and Well Being Risk Factors Heart Rate Atrial Fibrillation 80 and over Humans Female Retrospective Studies Aged |
| Zdroj: | Journal of the American Heart Association, vol 4, iss 4 |
| Popis: | BackgroundWhether heart rate upon discharge following hospitalization for heart failure is associated with long-term adverse outcomes and whether this association differs between patients with sinus rhythm (SR) and atrial fibrillation (AF) have not been well studied.Methods and resultsWe conducted a retrospective cohort study from clinical registry data linked to Medicare claims for 46 217 patients participating in Get With The Guidelines(®)-Heart Failure. Cox proportional-hazards models were used to estimate the association between discharge heart rate and all-cause mortality, all-cause readmission, and the composite outcome of mortality/readmission through 1 year. For SR and AF patients with heart rate ≥75, the association between heart rate and mortality (expressed as hazard ratio [HR] per 10 beats-per-minute increment) was significant at 0 to 30 days (SR: HR 1.30, 95% CI 1.22 to 1.39; AF: HR 1.23, 95% CI 1.16 to 1.29) and 31 to 365 days (SR: HR 1.15, 95% CI 1.12 to 1.20; AF: HR 1.05, 95% CI 1.01 to 1.08). Similar associations between heart rate and all-cause readmission and the composite outcome were obtained for SR and AF patients from 0 to 30 days but only in the composite outcome for SR patients over the longer term. The HR from 0 to 30 days exceeded that from 31 to 365 days for both SR and AF patients. At heart rates |
| Databáze: | OpenAIRE |
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