Psychological and neuropsychological advances in Motor neuron diseases: Amyotrophic lateral sclerosis and X-linked spinal-bulbar muscular atrophy
| Autor: | Grasso, Irene |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
amyotrophic lateral sclerosis
psychological intervention sclerosi laterale amiotrofica spinal and bulbar muscular atrophy intervento psicologico malattia del motoneurone executive functions atrofia muscolare spinobulbare MED/26 Neurologia malattia del motoneurone sclerosi laterale amiotrofica malattia di kennedy atrofia muscolare spinobulbare progressione di malattia funzioni esecutive intervento psicologico teoria della mente / motor neuron disease amyotrophic lateral sclerosis Kennedy’s disease spinal and bulbar muscular atrophy disease progression executive functions psychological intervention theory of mind disease progression funzioni esecutive teoria della mente / motor neuron disease malattia di kennedy Settore MED/26 - Neurologia Kennedy’s disease progressione di malattia theory of mind |
| Popis: | Motor neuron disease (MND) is a heterogeneous family of neurodegenerative diseases, rare, characterized by an early involvement of motor neurons and can be hereditary or sporadic, including Amyotrophic lateral sclerosis (ALS) and X-linked spinal-bulbar muscular atrophy (SBMA). Three studies will be briefly presented below, with the aim of developing an understanding of psychological and neuropsychological aspects in these diseases. In Chapter 3 is presented a retrospective study with the aim to verify whether the presence of cognitive impairment in ALS patients (according to the classification proposed by Phukan et al., 2012) may have an impact on the degree of disease progression in terms of motor decline. Up to date, in literature the debate about the influence of cognitive impairment on survival in ALS patients is still ongoing and results are conflicting. In summary, after 6 or 12 months follow up we observed the same degree of disease progression both in patients with presence or absence of cognitive impairment. In Chapter 4 it is presented a pilot study with the aim to investigate the applicability and efficacy of a hypnotic treatment on the physical and psychological well-being perceived by ALS patients, considering also the indirect effect on the well-being on caregivers. ALS implies an inevitable and devastating psychological impact and this study represent, even if at a preliminary level, the first application of a protocol of psychological intervention with evidence of efficacy in ALS patients. In Chapter 6, it is presented a study with the aim to investigate the neuropsychological and psychological profile in patients with SBMA, poorly characterized in the recent literature. In summary, in contrast with the previous literature, executive functioning seems to be apparently preserved in patients with SBMA; nevertheless patients seem to have a specific dysfunction on the cognitive component of the Theory of Mind (ToM), while the affective component seems to be preserved. |
| Databáze: | OpenAIRE |
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