Usporedba antibakterijske i antigljivične učinkovitosti otopina za dezinfekciju mekih kontaktnih leća

Autor: Tomislav Kuzman, Pokupec, R., Kalauz, M., Juri, J., Bujger, Z., Presečkl, A.
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Zdroj: Scopus-Elsevier
Acta clinica Croatica
Volume 47
Issue Supplement 1
ISSN: 0353-9466
1333-9451
Popis: Cilj studije bio je usporediti antibakterijska i antigljivična svojstva pet tekućina za dezinfekciju mekih kontaktnih leća. Ispitane su slijedeće tekućine: Oxysept Comfort (Advanced Medical Optics), Nitilens One Step (Avizor), Opti-Free Express (Alcon Laboratories), Complete Moisture Plus (Advanced Medical Optics) i Nitilens All-in-one (Avizor). Usporedili smo njihovu učinkovitost u dezinfekciji fiziološke otopine eksperimentalno kontaminirane slijedećim mikroorganizmima (American Type Culture Collection (ATCC)): Staphylococcus aureus (ATCC 25923), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853), Candida albicans (ATCC 90028) i Staphylococcus epidermidis (soj izoliran u našem laboratoriju). Sve ispitivane tekućine su smanjile početnu koncentraciju bakterija i gljivica ispod 1000 CFU/mL (broj kolonija/mL; smanjenje 3 log za bakterije i 1 log za gljivice) nakon dezinfekcijskog razdoblja od 8 sati. Međutim, zabilježene su razlike u njihovoj dezinfekcijskoj učinkovitosti. Općenito su sve ispitane tekućine pokazale dobru dezinfekcijsku učinkovitost protiv testiranih bakterija i gljivica, ali uočene razlike u njihovoj učinkovitosti mogu postati važne kod nesuradljivih nositelja mekih kontaktnih leća. Stoga su rezultati ove studije korisni pri odabiru tekućina kod navedene skupine nositelja.
The aim of this study was to compare antibacterial and antifungal efficacy of five soft contact lens disinfecting solutions. The following solutions were tested: Oxysept Comfort (Advanced Medical Optics), Nitilens One Step (Avizor), Opti-Free Express (Alcon Laboratories), Complete Moisture Plus (Advanced Medical Optics) and Nitilens All-in-one (Avizor). Their efficacy to disinfect saline solution experimentally contaminated with American Type Culture Collection (ATCC): Staphylococcus aureus (ATCC 25923), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853), Candida albicans (ATCC 90028) and Staphylococcus epidermidis (isolated from our laboratory) was tested. All study solutions reduced concentrations of bacteria and fungi below 1000 CFU/mL (reduction by 3 log and 1 log, respectively) after 8-hour overnight disinfection. However, there were differences in their disinfecting efficacy. Generally, all contact lens care solutions showed good disinfecting activity against the bacteria and fungi tested. Yet, the differences recorded in their antimicrobial activity may become more evident among non-compliant patients, and therefore the results of the study might be valuable when selecting appropriate solutions for contact lens wearers.
Databáze: OpenAIRE
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