Otoacoustic emissions in children treated with gentamicin in a secondary hospital
| Autor: | Sequi Canet JM, ANGELATS C, Sequi Sabater JM, Miralles Torres A, Boronat Garcia M, Gomez Delgado M |
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| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Acta Otorrinolaringologica Espanola r-FISABIO: Repositorio Institucional de Producción Científica Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO) r-FISABIO. Repositorio Institucional de Producción Científica instname |
| ISSN: | 0001-6519 |
| Popis: | Introduction: The National Commission for the Early Detection of Hearing Loss (CODEPEH) recommends the re-evaluation of hearing in children who have suffered any potentially harmful event, such as the prescription of ototoxic antibiotics such as gentamicin. The evoked otoacoustic emissions (EOAE) are a good method for assessing the integrity of cochlear functionality. Material and method: A prospective study is presented, including 92 children who were treated with intravenous gentamicin for septic risk/sepsis or urinary tract infection. The children underwent serial EOAE: on admission, at the end of treatment and one month later (if altered on discharge). Results: In the end, none of the subjects were affected by the treatment. Conclusion: Gentamicin appears to be a safe antibiotic in treatments lasting < 10 days and at the doses described. EOAE are an inexpensive, fast, non-invasive and reliable method to check for gentamicin ototoxicity. This could save in the determination of drug levels. (C) 2018 Sociedad Espanola de Otorrinolaringologia y Cirugia de Cabeza y Cuello. Published by Elsevier Espana, S.L.U. All rights reserved. |
| Databáze: | OpenAIRE |
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