Effect of Local Puerarin Administration on Xenograft
| Autor: | Turer, Akif, Turer, Cigdem Coskun, Onger, Mehmet Emin |
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| Přispěvatelé: | Zonguldak Bülent Ecevit Üniversitesi, OMÜ |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Popis: | WOS: 000423935700009 Aim: The purpose of this study was to investigate the healing potential of local puerarin administration on xenograft in cranial bone defect treatment in rats. Material and Method: A critical-size defect of 5-mm diameter was created in the calvarium of twenty-four rats. The animals were divided into three groups: group C (passive control), group XBG (treated with Bio-Oss), and group P-XBG (treated with puerarin + Bio-Oss combination). All animals were euthanized at 28 days postoperative. Stereologic analyses were performed. New bone area and connective tissue volumes were measured. Results: Mean new bone volumes were 1.57 +/- 0.13mm3, 1.24 +/- 0.10 mm3, and 0.31 +/- 0.09 mm3 in groups P-XBG, XBG and C respectively. The new bone volumes were statistically significant in groups P-XBG and XBG compared to group C (p |
| Databáze: | OpenAIRE |
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