SEASONAL CHANGES AND MORNING BLOOD PRESSURE SURGE. WHICH ROLE FOR OUTDOOR AND INDOOR AIR TEMPERATURE?

Autor: Modesti, P., Morabito, M., Massetti, L., Cambi, G. E., Bilo, G., Caldara, G., simone orlandini, Mancia, G., Gensini, G. F., Parati, G.
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Zdroj: ResearcherID
20th European meeting on Hypertension, pp. 29.147–29.147, Oslo, 2010
info:cnr-pdr/source/autori:Modesti, P(1); Morabito, M(2,3); Massetti, L(3); Cambi, GE(1); Bilo, G(4,5); Caldara, G(5); Orlandini, S(2); Mancia, G(4); Gensini, GF(1,2); Parati, G(4,5)/congresso_nome:20th European meeting on Hypertension/congresso_luogo:Oslo/congresso_data:2010/anno:2010/pagina_da:29.147/pagina_a:29.147/intervallo_pagine:29.147–29.147
Popis: Objective: Important climate related variations of clinic and ambulatory blood pressure (BP) have been repeatedly reported. However, notwithstanding the wide use of indoor climate control systems, specially in winter, no information is available regarding the role of air temperature values measured proximally to the patient, in particular when focussing on specific components of the 24 h BP profile, such as the morning BP surge (MBPS). Design and Methods: To investigate whether MBPS is affected by outdoor air temperature or by the air temperature measured proximally to the patient, 2120 hypertensives underwent 24 h ambulatory blood pressure (ABP) monitoring with a battery-powered "HOBO" temperature data logger fitted to the carrying pouch of the ABP monitor. Predictors of MBPS were investigated with a multivariate stepwise regression model including age, gender, body mass index, office systolic BP, 24 h average ABP, mean 24 h outdoor atmospheric pressure and mean 24 h air temperature measured both outdoor and by HOBO as independent variables. Results: Stepwise multiple regression analysis carried out in the 1728 subjects included in the final analysis selected outdoor air temperature(beta = -0.09;p < 0.0001), 24 h ABP(beta = -0.72;p < 0.0001), and age(beta = -0.06;p < 0.002) as negative independent predictors of MBPS, with systolic office BP selected as a positive independent predictor (beta = 1,04;p < 0.0001)(r = 0.610); no significant effect of HOBO air temperature was observed. When subjects were stratified according to age, the effect on MBPS of outdoor air temperature was detectable in subjects >65 yrs (beta = -0.086; p < 0.002), whereas the only determinants of MBPS in subjects < 50 yrs were office SBP (positive) and 24 h average SBP(negative). Conclusions: These results confirm and extend previous observation on the occurrence of seasonal changes in 24 h BP profiles, by providing new evidence that only air temperature measured outdoor affects BP morning surge in addition to office BP, 24 h ABP and age, whereas no role appears to be played by air temperature measured proximally to the patient. The clinical implications of these findings for BP control would need to be further tested by ad hoc studies.
Databáze: OpenAIRE
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