Clinical aspects of non-severe hemophilia: Focus on bleeding, joint and treatment outcomes
| Autor: | Kloosterman, F.R. |
|---|---|
| Přispěvatelé: | Fijnvandraat, C.J., Gouw, S.C., Coppens, M., Faculteit der Geneeskunde |
| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Popis: | Hemophilia A and B are rare inherited bleeding disorders, caused by mutations in the F8 or F9 gene on the X-chromosome leading to a deficiency of coagulation factor VIII (FVIII) or coagulation factor IX (FIX), respectively. As a result, persons with decreased coagulation FVIII/IX levels have an increased bleeding tendency. Classification of disease severity is based on the endogenous FVIII/IX level, ranging from severe (FVIII/IX |
| Databáze: | OpenAIRE |
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