Malaria Parasitemia and Nutritional Status during the Low Transmission Season in the Presence of Azithromycin Distribution among Preschool Children in Niger
| Autor: | Arzika, Ahmed M, Maliki, Ramatou, Boubacar, Nameywa, Kane, Salissou, Cook, Catherine A, Lebas, Elodie, Lin, Ying, O'Brien, Kieran S, Austin, Ariana, Keenan, Jeremy D, Lietman, Thomas M, Oldenburg, Catherine E, For The Mordor Study Group |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Clinical Trials and Supportive Activities Nutritional Status Azithromycin Parasitemia Medical and Health Sciences Rare Diseases Clinical Research Tropical Medicine parasitic diseases Humans Niger Child Preschool Nutrition Pediatric Prevention Evaluation of treatments and therapeutic interventions Infant Malaria Anti-Bacterial Agents Vector-Borne Diseases Infectious Diseases Good Health and Well Being 6.1 Pharmaceuticals Mass Drug Administration Zero Hunger Female Seasons Infection |
| Zdroj: | The American journal of tropical medicine and hygiene, vol 103, iss 3 |
| Popis: | The relationship between malaria and malnutrition is complicated, and existence of one may predispose or exacerbate the other. We evaluated the relationship between malaria parasitemia and nutritional status in children living in communities participating in a cluster-randomized trial of biannual azithromycin compared with placebo for prevention of childhood mortality. Data were collected during the low malaria transmission and low food insecurity season. Parasitemia was not associated with weight-for-height Z-score (24 months: P = 0.11 azithromycin communities, P = 0.75 placebo communities), weight-for-age Z-score (24 months: P = 0.83 azithromycin, P = 0.78 placebo), height-for-age Z-score (24 months: P = 0.30 azithromycin, P = 0.87 placebo), or mid-upper arm circumference (24 months: P = 0.12 azithromycin, P = 0.56 placebo). There was no statistically significant evidence of a difference in the relationship in communities receiving azithromycin or placebo. During the low transmission season, there was no evidence that malaria parasitemia and impaired nutritional status co-occur in children. |
| Databáze: | OpenAIRE |
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