Benefits and harm of systemic steroids for short- and long-term use in rhinitis and rhinosinusitis: an EAACI position paper

Autor: Hox, Valerie, Lourijsen, Evelijn, Jordens, Arnout, Aasbjerg, Kristian, Agache, Ioana, Alobid, Isam, Bachert, Claus, Boussery, Koen, Campo, Paloma, Fokkens, Wytske, Hellings, Peter, Hopkins, Claire, Klimek, Ludger, Makelä, Mika, Moesges, Ralph, Mullol, Joaquim, Pujols, Laura, Rondon, Carmen, Rudenko, Michael, Toppila-Salmi, Sanna, Scadding, Glenis, Scheire, Sophie, Tomazic, Peter-Valentin, Van Zele, Thibaut, Wagemann, Martin, van Boven, Job F. M., Gevaert, Philippe
Přispěvatelé: [Hox,V] Cliniques Universitaires Saint-Luc Brussels, Brussels, Belgium. [Lourijsen,E, Fokkens,W] Department of Otorhinolaryngology, Amsterdam University Medical Centres, AMC, Amsterdam, The Netherlands. [Jordens,A, Bachert,C, Van Zele,T, Gevaert,P] Upper Airway Research Laboratory, Dep. of Otorhinolaryngology, Ghent University Hospital, Ghent, Belgium. [Aasbjerg,K] Bispebjerg University Hospital, Copenhagen, Denmark. [Agache,I] Faculty of Medicine, Transsylvania University, Brasov, Romania. [Alobid,I, Mullol,J, Pujols,L] Hospital Clínic, IDIBAPS, CEBERES Universitat de Barcelona, Catalonia, Spain. [Alobid,I] Centro Medico Teknon, Barcelona, Spain. [Bachert,C] Department of Ear, Nose and Throat Diseases, Karolinska University Hospital, Stockholm, Sweden. [Boussery,K, Scheire,S] Pharmaceutical Care Unit, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium. [Campo,P, Rondon,C] Allergy Unit, Hospital Regional Universitario of Málaga, IBIMA, ARADyAL, Malaga, Spain. [Hellings,P] Department of Ear, Nose and Throat Disease, University Hospitals, Louvain, Belgium. [Hopkins,C] ENT Department, Guy’s & St Thomas’ Hospital, London, UK. [Klimek,L] Center of Rhinology and Allergology, Wiesbaden, Germany. [Mäkelä,M, Toppila‑Salmi,S] Skin and Allergy Hospital, Helsinki University Hospital and University of Helsinki, Helsinki, Finland. [Mösges,R] University of Cologne, Cologne, Germany. [Rudenko,M] London Allergy and Immunology Center, London, UK. [Scadding,G] Royal National Throat, Nose and Ear Hospital, London, UK. [Tomazic,PV] Medical University Graz, Graz, Austria. [Wagemann,M] Heinrich-Heine-University, Düsseldorf, Germany. [van Boven,JFM] Department of Clinical Pharmacy & Pharmacology, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, Groningen, The Netherlands., This work was funded by an EAACI Task Force budget., HUS Inflammation Center, Department of Dermatology, Allergology and Venereology, University of Helsinki
Jazyk: angličtina
Rok vydání: 2020
Předmět:
SEASONAL ALLERGIC RHINITIS
Rhinosinusitis
Diseases::Otorhinolaryngologic Diseases::Nose Diseases::Rhinitis [Medical Subject Headings]
Diseases::Otorhinolaryngologic Diseases::Nose Diseases::Nasal Polyps [Medical Subject Headings]
Pólipos nasales
Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]
DOUBLE-BLIND
WEGENERS-GRANULOMATOSIS
ORAL STEROIDS
SEVERE NASAL POLYPOSIS
Sinusitis
Glucocorticoides
Rinitis
Corticoesteroides
Rhinitis
CORTICOSTEROID-THERAPY
Diseases::Otorhinolaryngologic Diseases::Nose Diseases::Paranasal Sinus Diseases::Sinusitis [Medical Subject Headings]
Chemicals and Drugs::Hormones
Hormone Substitutes
and Hormone Antagonists::Hormones::Adrenal Cortex Hormones [Medical Subject Headings]

Glucocorticosteroids
RHEUMATOID-ARTHRITIS
Chemicals and Drugs::Hormones
Hormone Substitutes
and Hormone Antagonists::Hormones::Adrenal Cortex Hormones::Glucocorticoids [Medical Subject Headings]

3121 General medicine
internal medicine and other clinical medicine

GLUCOCORTICOID-RECEPTOR-ALPHA
BONE-MINERAL DENSITY
ENDOSCOPIC SINUS SURGERY
Popis: Correction: Volume: 10 Issue: 1 Article Number: 38 DOI: 10.1186/s13601-020-00343-w Published: SEP 28 2020 Because of the inflammatory mechanisms of most chronic upper airway diseases such as rhinitis and chronic rhinosinusitis, systemic steroids have been used for their treatment for decades. However, it has been very well documented that-potentially severe-side-effects can occur with the accumulation of systemic steroid courses over the years. A consensus document summarizing the benefits of systemic steroids for each upper airway disease type, as well as highlighting the potential harms of this treatment is currently lacking. Therefore, a panel of international experts in the field of Rhinology reviewed the available literature with the aim of providing recommendations for the use of systemic steroids in treating upper airway disease.
Databáze: OpenAIRE