The International Prostate Symptom Score (IPSS) Is an Inadequate Tool to Screen for Urethral Stricture Recurrence After Anterior Urethroplasty

Autor: Tam, Christopher A, Elliott, Sean P, Voelzke, Bryan B, Myers, Jeremy B, Vanni, Alex J, Breyer, Benjamin N, Smith, Thomas G, McClung, Christopher D, Erickson, Bradley A, Trauma and Urologic Reconstruction Network of Surgeons (TURNS)
Rok vydání: 2016
Předmět:
Zdroj: Tam, CA; Elliott, SP; Voelzke, BB; Myers, JB; Vanni, AJ; Breyer, BN; et al.(2016). The International Prostate Symptom Score (IPSS) Is an Inadequate Tool to Screen for Urethral Stricture Recurrence After Anterior Urethroplasty. UROLOGY, 95, 197-201. doi: 10.1016/j.urology.2016.04.006. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/20b9s23h
Popis: ObjectiveTo validate the use of the International Prostate Symptom Score (IPSS) as a stand-alone tool to detect urethral stricture recurrence following urethroplasty.Materials and methodsThis study included 393 men who had undergone anterior urethroplasty and were enrolled in a multi-institutional outcomes study. Data analyzed included pre- and post-operative answers to the IPSS in addition to findings from a same- day cystoscopy. IPSS from men found to have cystoscopic recurrence were then compared to scores from those with successful repairs, and receiver operating characteristic curves were plotted to illustrate the predictive ability of these questions to screen for cystoscopic recurrence.ResultsMean postoperative scores were lower (fewer symptoms) in successful repairs; IPSS improved from preoperative values regardless of recurrence. Successful repairs had significantly better degree of improvement in question #5 (assessing weak stream) compared to recurrences. Receiver operating characteristic curves demonstrated the highest area under the curve for the IPSS quality of life question (0.66) that alone outperformed the complete IPSS questionnaire (0.56).ConclusionThe IPSS had inadequate sensitivity and specificity to be used as a stand-alone screening tool for stricture recurrence in this large cohort of men, highlighting the need to continue development of a disease-specific, validated patient-reported outcome measure.
Databáze: OpenAIRE