JAPANESE QUAIL (COTURNIX JAPONICA) AS THE MODEL OF HUMAN AGING RETINAL PROCESSES. REPORT № 2. COMPARATIVE ANALYSIS OF THE COMPOSITION OF RETINOIDS ISOLATED FROM RETINAL PIGMENT EPITHELIUM OF HUMAN AND JAPANESE QUAIL EYES

Autor:	M.A. Yakovleva, A.V. Zykova, P.M. Arbuhanova, N.N. Trofimova, S.A. Borzenok, M.A. Ostrovsky, P.P. Zak
Jazyk:	ruština
Rok vydání:	2015
Předmět:	Ophthalmology lcsh:Ophthalmology retinoids lcsh:RE1-994 ageing retinal pigment epithelium lipofuscin granules japanese quail sense organs RE1-994 eye diseases
Zdroj:	Офтальмохирургия, Vol 0, Iss 2, Pp 47-51 (2015) Офтальмохирургия, Iss 2, Pp 47-51 (2013)
ISSN:	2312-4970 0235-4160
Popis:	Purpose. To compare the composition of retinoids of lipofuscin granules (LG) isolated from retinal pigment epithelium (RPE) of human cadaver eyes and Japanese quail. Material and methods. The Japanese quail′s retina and retinal pigment epithelium were chosen as a model of laboratory aging simulation. The evaluation of the amount of quail′s RPE retinoids was done by measuring of the fluorescence spectra and HPLC-analysis of the chloroform- methanol extraction from PRE. Results and conclusions. It has been shown that the spectral characteristics and the relative content of retinoids in lipofuscin granules (LG) isolated from retinal pigment epithelium (RPE) of human cadaver eyes and Japanese quail was very resemblance. These results allowed to consider Japanese quail (Coturnix japonica) as a suitable and enough adequate model of rapid human aging retinal processes
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::50ea383a639e7d5ff08cca6561c948ff https://www.ophthalmosurgery.ru/jour/article/view/154 Zobrazit plný text záznamu